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當前位置:首頁技術文章VPREB1抗原,B淋巴細胞前體蛋白1抗原

VPREB1抗原,B淋巴細胞前體蛋白1抗原

更新時間:2024-11-18點擊次數(shù):199

Recombinant human VPREB1 protein   

CD179 antigen like family member A; CD179 antigen-like family member A; CD179a; IGI; IGVPB; Immunoglobulin iota chain; Pre B lymphocyte 1; pre-B lymphocyte 1; Protein VPreB1; V(pre)B protein; VPREB 1; VPREB; VpreB protein; VPREB_HUMAN; VPREB1.  

濃度:1mg/ ml

來源:Recombinant Human

純度:95% SDS-PAGE

表達系統(tǒng):Escherichia coli

標簽:His tag

蛋白長度:Full length protein

內(nèi)毒素水平:<1.000 Eu/µg

純化方法:HPLC

應用:SDS-PAGE,Western blotELISA

Biological activity,immunology research

保存:-20

保質(zhì)期:1

VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit.



產(chǎn)品名稱:Rabbit Anti-VPREB1 protein antibody

Rabbit Anti-VPREB1 protein 

別名:CD179 antigen like family member A; CD179 antigen-like family member A; CD179a; IGI; IGVPB; Immunoglobulin iota chain; Pre B lymphocyte 1; pre-B lymphocyte 1; Protein VPreB1; V(pre)B protein; VPREB 1; VPREB; VpreB protein; VPREB_HUMAN; VPREB1.            

來源:Rabbit

克隆類型:Polyclonal

濃度:1mg/ml

亞型:IgG

反應:(predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)

應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500  Flow-Cyt=3ug/Test

理論分子量:15 kDa

免疫原:KLH conjugated synthetic peptide derived from human VPREB1 protein

保存:-20
保質(zhì)期:1

 

 

產(chǎn)品名稱:Anti-VPREB1 protein antibody

Mouse Anti-VPREB1 protein

別名:CD179 antigen like family member A; CD179 antigen-like family member A; CD179a; IGI; IGVPB; Immunoglobulin iota chain; Pre B lymphocyte 1; pre-B lymphocyte 1; Protein VPreB1; V(pre)B protein; VPREB 1; VPREB; VpreB protein; VPREB_HUMAN; VPREB1.              

來源:Mouse

克隆類型:Monoclonal

濃度:1mg/ml

亞型:IgG

反應:Human

應用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500 Flow-Cyt=3ug/Test

反應:  Human

理論分子量:15 kDa

免疫原:KLH conjugated synthetic peptide derived from human VPREB1 protein

保存:-20
保質(zhì)期:1

VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit.


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